Mouse Sphingosine kinase 2 (Sphk2) ELISA Kit

Assay Genie's sandwich ELISA kit enables quantitative detection of mouse Sphingosine kinase 2 (SPHK2) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay uses a colorimetric detection method, is reactive with mouse samples, and is specific for natural and recombinant mouse Sphingosine kinase 2.

Performance specifications include a detection range of 78-5000pg/mL and a sensitivity of 40pg/mL, supporting accurate and reproducible measurement of SPHK2 levels in research applications. SPHK2 plays a key role in sphingolipid metabolism, catalyzing the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. The enzyme also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine, and binds phosphoinositides. Subcellular localization is the lysosome membrane, and the kit is associated with cardiovascular research.

Dysregulation of SPHK2 has been implicated in various diseases, including cancer, inflammatory disorders and neurological conditions, making accurate measurement of the enzyme important for studies of disease progression and targeted therapies. For research use only.