Mouse SOST (Sclerostin) ELISA Kit (MOFI01429)

Sclerostin is a glycoprotein secreted predominantly by osteocytes that acts as a negative regulator of the Wnt/β-catenin signaling pathway, making it a critical biomarker in bone metabolism research. This quantitative ELISA from Assay Genie enables measurement of mouse Sclerostin concentrations in support of investigations into bone formation, bone resorption, osteoporosis models, and genetic skeletal disorders such as sclerosteosis and van Buchem disease.

The kit provides all components required to perform the immunoassay, including a pre-coated microplate, lyophilized standards, biotinylated detection antibody, streptavidin-HRP conjugate, wash buffer, substrate solution, and stop reagent. Mouse samples and cell culture supernatant preparations can be analyzed. Reconstituted reagents should be stored refrigerated when not in use.

Intended for research use only, this 96 Assays immunoassay supports bone biology laboratories, endocrinology research, and preclinical drug development programs investigating Wnt pathway modulators and anti-sclerostin therapeutic candidates.