Mouse Somatotropin (Gh1) ELISA Kit

A competitive ELISA from Assay Genie designed for the precise measurement of somatotropin, also known as growth hormone, in mouse serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Somatotropin plays a crucial role in regulating growth, metabolism, and overall health in mammals, and abnormal levels are associated with growth disorders, metabolic disorders, and obesity, making it a valuable biomarker for research.

The kit has a detection range of 0.156-10ng/mL with a sensitivity of 0.078ng/mL. Intra-assay CV is 4.1% and inter-assay CV is 6.4%. Linearity has been validated across serum, EDTA plasma, and heparin plasma samples at dilutions of 1:2, 1:4, 1:8, and 1:16. Recovery averages 81% (range 80-87%) for serum and 83% (range 80-89%) for plasma. The assay shows specificity for natural and recombinant mouse somatotropin and is intended for research use only within the Signal Transduction research area.

The target protein (UniProt: P06880, NCBI gene symbol Gh/Gh1) is a secreted hormone that functions to stimulate body growth by promoting IGF-1 secretion from the liver, stimulating myoblast differentiation and proliferation, and enhancing amino acid uptake and protein synthesis in muscle and other tissues.