Mouse Smad7 (Mothers Against Decapentaplegic Homolog 7) ELISA Kit (MOES01483)

Smad7 is an inhibitory member of the SMAD family that antagonizes transforming growth factor-beta signaling by blocking receptor-mediated phosphorylation of receptor-regulated SMADs. As a key negative-feedback regulator of TGF-β pathways, Smad7 sits at the intersection of fibrosis research, inflammatory disease models, epithelial injury repair, and tumor suppressor investigations in murine systems. Researchers studying chronic kidney disease, liver fibrogenesis, colitis phenotypes, or knockout mice routinely quantify Smad7 protein levels in tissue homogenates and lysates prepared from mouse models of disease.

This Assay Genie microplate-based immunoassay kit is intended for research use only and supports quantitation of endogenous mouse Smad7 across common murine sample matrices including circulatory fluid and tissue-derived preparations. Each kit provides reagents for 96 individual determinations, accommodating full-plate experimental layouts or smaller replicate sets. The workflow is compatible with standard cell culture supernatant analysis and in vivo model investigations where TGF-β pathway inhibition, BMP signaling crosstalk, or downstream transcriptional regulation are being characterized.