Mouse Sialidase 2, Cytosolic (SIAL2) ELISA Kit

Sialidase 2 (NEU2) is a cytosolic glycosidase that hydrolyzes terminal sialic acid residues from glycoproteins and glycolipids, and researchers use mouse-specific immunoassays to quantify its expression across tissues. This Assay Genie kit targets the cytosolic isoform rather than the lysosomal (NEU1) or membrane-associated (NEU3, NEU4) enzymes, making it useful for studies of skeletal muscle differentiation, neuronal metabolism, and lysosomal storage disorders where altered sialylation is implicated.

The kit includes a pre-coated microplate, detection antibody, standards, and substrate sufficient for 96 determinations, with all reagents shipped for storage at -20 °C and the diluted wash buffer stable at room temperature. Researchers typically apply this ELISA to investigate NEU2 regulation in knockout models, to compare cytosolic sialidase activity across mouse strains, or to validate transcriptomic findings at the protein level using tissue homogenates.