Mouse Sestrin 2 (SESN2) ELISA Kit

Quantitative measurement of mouse Sestrin 2 protein in research samples is supported by this immunoassay kit from Assay Genie. Sestrin 2 is a highly conserved stress-inducible protein that regulates cellular homeostasis under oxidative stress, DNA damage, and nutrient deprivation conditions. It functions as a key modulator of AMPK activation and mTORC1 inhibition, linking metabolic control to protective responses. The protein has emerged as a focal point in studies of aging, neurodegeneration, insulin resistance, hepatic steatosis, and tumor suppression pathways.

Each kit provides reagents for 96 individual determinations and is validated for mouse-derived samples including tissue homogenates. The protocol produces a measurable absorbance-based signal proportional to SESN2 concentration, allowing quantification on standard laboratory microplate readers. Typical workflow involves coating, incubation, washing, and substrate development steps common to solid-phase immunoassays. The format accommodates both small exploratory studies and larger experimental cohorts examining SESN2 dynamics across treatment groups or genetic backgrounds.

Assay Genie manufactures the reagents under standardized quality controls to support reproducibility across experimental batches. The Mouse SESN2 kit is intended for research use only and should not be used for clinical or diagnostic purposes. For specific protocol details, recommended sample preparation, and reagent storage conditions, refer to the enclosed product documentation.