Mouse Semaphorin-5A (Sema5a) ELISA Kit

Designed by Assay Genie for the accurate detection of mouse Semaphorin-5A (Sema5A) levels in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, this sandwich ELISA delivers high sensitivity and specificity for research applications. Sema5A is a member of the semaphorin family known for its role in regulating neuronal development, axon guidance, and synaptic connectivity, and has been implicated in neurological disorders including autism spectrum disorders and schizophrenia.

The assay provides a detection range of 0.312–20 ng/mL with a sensitivity of 0.188 ng/mL and is specific for natural and recombinant mouse Semaphorin-5A. The target is a single-pass type I membrane protein that acts as a bifunctional axonal guidance cue regulated by sulfated proteoglycans, producing attractive effects via heparan sulfate proteoglycans and inhibitory effects via chondroitin sulfate proteoglycans, and binds the receptor PLXNB3. For research use only.