Mouse Ribonucleoside-diphosphate reductase large subunit (Rrm1) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is designed for the quantitative detection of mouse Ribonucleoside-diphosphate reductase large subunit (Rrm1) in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. The assay demonstrates specificity for natural and recombinant mouse Rrm1 and supports accurate, reproducible measurement across a range of research workflows.

Rrm1 (also listed as Ribonucleoside-diphosphate reductase subunit M1 and Ribonucleotide reductase large subunit) is an essential enzyme that provides the precursors necessary for DNA synthesis by catalysing the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. The protein localises to the cytoplasm (UniProt P07742) and falls within the Epigenetics research area. Dysregulation of Rrm1 has been linked to cancer and other diseases, making it a valuable biomarker for studying these conditions and developing potential treatments.

Performance characteristics include a detection range of 0.156–10 ng/mL and a sensitivity of 0.091 ng/mL. Intra-assay CV, inter-assay CV, linearity and recovery values are provided with the kit. For research use only.