Mouse Rho GTPase-activating protein 21 (Arhgap21) ELISA Kit

This sandwich ELISA from Assay Genie is designed for the quantitative measurement of mouse Rho GTPase-activating protein 21 (Arhgap21) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay shows specificity for natural and recombinant mouse Arhgap21.

Reported performance characteristics include a sensitivity of 40.6 pg/mL and a detection range of 78-5000 pg/mL. The target protein, Arhgap21, is a GTPase-activating protein (GAP) for RHOA and CDC42 that functions as a downstream partner of ARF1 and is required for CTNNA1 recruitment to adherens junctions.

ARHGAP21 is a key regulator of Rho GTPase activity, involved in cell migration, adhesion, and cytoskeletal organization. Dysregulation has been implicated in diseases including cancer, immune disorders, and neurological disorders, supporting the kit's relevance for research investigating these conditions and potential biomarkers.