Mouse Retinoblastoma-like protein 1 (Rbl1) ELISA Kit

A sandwich ELISA kit from Assay Genie designed for the quantitative detection of mouse Retinoblastoma-like protein 1 (RBL1) in mouse samples. The assay provides a detection range of 0.78-50ng/mL with a sensitivity of 0.407ng/mL, and exhibits specificity for natural and recombinant mouse RBL1. The target is also known by the synonyms 107 kDa retinoblastoma-associated protein, pRb1, and p107.

Compatible sample types include serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. RBL1 functions as a key regulator of entry into cell division and a potent inhibitor of E2F-mediated trans-activation, with roles in heterochromatin formation and in controlling histone H4 'Lys-20' trimethylation. The protein localises to the nucleus, and the isoform covered by the kit (retinoblastoma-like protein 1 isoform 2) is associated with the UniProt entry Q64701, with a reported molecular weight of 67,497 Da. For research use only.