Mouse Renin 1 PharmaGenie ELISA Kit (SBRS1515)

Quantitative measurement of mouse renin (REN1) supports research into the renin-angiotensin system, a hormonal cascade central to blood pressure regulation, fluid-electrolyte balance, and cardiovascular pathophysiology. The Assay Genie Mouse Renin 1 PharmaGenie ELISA Kit is a research-use-only immunoassay developed for this purpose, enabling investigators to quantify renin concentrations in laboratory specimens. Renin is an aspartyl protease that catalyzes the rate-limiting step of the renin-angiotensin cascade by cleaving angiotensinogen to generate angiotensin I, and is a focal target in studies of hypertensive disease, renal function, and pharmacological modulation of the RAS pathway. The assay accepts murine plasma, serum samples, and conditioned cell culture medium, making it applicable to work in transgenic and knockout mouse models as well as pharmacological screening campaigns. Detection proceeds colorimetrically in a 96-assay plate layout appropriate for medium-throughput experimental workflows. Each kit includes pre-coated microplate wells, assay buffers, detection reagents, and a standard curve for interpolating renin concentrations in unknown samples. Investigators studying salt-sensitive hypertension, diabetic nephropathy, or compounds targeting angiotensin-converting enzyme and related effectors routinely employ this assay to track circulating or tissue-level renin concentrations in murine experimental systems.