Mouse Regenerating Islet Derived Protein 3 Alpha (REG3a) ELISA Kit

Used to quantify a key antimicrobial lectin in mouse models, this Assay Genie kit targets Regenerating Islet Derived Protein 3 Alpha (REG3a), a C-type lectin secreted by intestinal epithelial cells and pancreatic acinar cells. REG3a contributes to mucosal barrier defense by binding bacterial peptidoglycan and limiting colonization by Gram-positive commensals, making it a relevant readout for studies of pancreatitis, inflammatory bowel disease, gut microbiome dysbiosis, and host-microbe signaling. The colorimetric immunoassay is read on a standard well plate, and components should be kept refrigerated to preserve binding activity across the full assay run. Researchers investigating REG3A gene regulation, RegIIIγ ortholog biology, or downstream IL-22/STAT3 signaling in the small intestine can use this kit for time-course comparisons in cell culture supernatants and tissue homogenates.