Mouse Receptor-type tyrosine-protein phosphatase C (Ptprc) ELISA Kit

From Assay Genie, this sandwich ELISA enables quantitative measurement of mouse Receptor-type tyrosine-protein phosphatase C (Ptprc), also known as CD45. The assay is specific for natural and recombinant mouse Ptprc and is intended for research use only.

Ptprc is a receptor-type protein tyrosine phosphatase specifically expressed in hematopoietic cells. It is required for T-cell activation through the antigen receptor and is a critical enzyme involved in immune response regulation, making it a valuable biomarker for studying immune function and inflammatory diseases in mouse models. The kit supports applications across immunology, cancer biology, and autoimmune disease research using serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids.

The reported detection range is 0.156-10ng/mL with a sensitivity of 0.065ng/mL. The target protein is localised at the membrane as a single-pass type I membrane protein found in membrane rafts, colocalised with DPP4.