Mouse Receptor-interacting serine/threonine-protein kinase 2 (Ripk2) ELISA Kit

Manufactured by Assay Genie, this Sandwich ELISA Kit is designed for quantitative detection of Mouse Receptor-interacting serine/threonine-protein kinase 2 (Ripk2), also listed under the synonym Tyrosine-protein kinase RIPK2. The assay is reactive with mouse samples and targets the RIPK2 protein referenced under UniProt P58801, supporting research within the immunology field.

Validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, the kit employs a colorimetric ELISA detection method. Reported performance figures include a detection range of 0.156–10 ng/mL and a sensitivity of 0.082 ng/mL, with specificity for natural and recombinant mouse Receptor-interacting serine/threonine-protein kinase 2.

RIPK2 is a serine/threonine/tyrosine kinase that plays an essential role in modulating innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerise and recruit RIPK2 through CARD-CARD domains, triggering NF-kappa-B activation and downstream processes including cytokine production, apoptosis regulation and T-cell receptor signalling. The kit is supplied for research use only, with components stored at -20°C and shipped at +4°C.