Mouse Pyruvate Dehydrogenase Beta (PDHb) ELISA Kit

Quantitative measurement of the pyruvate dehydrogenase E1 component subunit beta (PDHB) in murine samples supports research into mitochondrial energy metabolism and related disease mechanisms. The reagents from Assay Genie target the E1β catalytic subunit of the pyruvate dehydrogenase complex, the mitochondrial enzyme system that decarboxylates pyruvate to generate acetyl-CoA for entry into the tricarboxylic acid cycle.

Investigators studying the Warburg effect in cancer cell metabolism, lactic acidosis linked to PDH deficiency, and neural metabolic dysfunction use this reagent to quantify PDHB protein levels in mouse tissue homogenates and cell lysates. Each kit provides reagents sufficient for 96 determinations in a microplate format with a colorimetric readout, supporting laboratory workflows that investigate glycolytic flux regulation and TCA cycle coupling in murine models.