Mouse Pyruvate Dehydrogenase Alpha (PDHa) ELISA Kit

Pyruvate dehydrogenase alpha (PDHα) is the catalytic E1 subunit of the mitochondrial pyruvate dehydrogenase complex, the rate-limiting enzyme that links glycolysis to the citric acid cycle by converting pyruvate to acetyl-CoA.

The Mouse Pyruvate Dehydrogenase Alpha (PDHa) ELISA Kit from Assay Genie enables quantitative measurement of PDHα protein in mouse-derived research specimens. Supplied as a 96-assay kit with a colorimetric readout compatible with standard absorbance readers, this kit is validated for serum, tissue homogenates, cell lysates, and plasma samples collected from murine models.

Researchers in metabolic disease, mitochondrial biology, and cancer metabolism employ this assay to investigate PDH regulation, phosphorylation by PDH kinase, and altered glucose oxidation in conditions such as type 2 diabetes, neurodegeneration, and tumor bioenergetics. Each kit contains a pre-coated microplate, detection antibody, standards, substrate, and buffers sufficient for 96 determinations, supporting applications in cell culture supernatant analysis, in vitro enzyme regulation studies, and in vivo investigations of mouse model phenotypes.