Mouse Prothyroliberin (Trh) ELISA Kit

From Assay Genie, this sandwich ELISA kit is designed for the precise measurement of mouse prothyroliberin (also known as thyrotropin-releasing hormone, TRH) levels. The target protein plays a crucial role in regulating thyroid hormone secretion and other physiological processes, and aberrant TRH levels have been linked to thyroid diseases and neurological disorders, making it a useful biomarker for research applications.

The kit uses a colorimetric detection method and is reactive with mouse samples. It detects natural and recombinant mouse pro-thyrotropin-releasing hormone with a detection range of 78-5000pg/mL and a sensitivity of 39pg/mL. Compatible sample types include serum, plasma, tissue homogenates, and cell culture supernatants, with the target localised to the secreted cellular compartment. The associated UniProt entry is Q62361.

Functionally, prothyroliberin acts as a regulator of TSH biosynthesis in the anterior pituitary gland and serves as a neurotransmitter/neuromodulator in the central and peripheral nervous systems. The kit is intended for research use only.