Mouse Progesterone receptor (Pgr) ELISA Kit

Designed by Assay Genie, this Sandwich ELISA Kit enables the quantitative measurement of mouse progesterone receptor (Pgr). The target is a nuclear hormone receptor and transcription factor that mediates the physiological effects of progesterone and plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.

Validated sample types include serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay is specific for natural and recombinant mouse progesterone receptor and operates across a detection range of 0.312-20ng/mL with a sensitivity of 0.173ng/mL. Listed synonyms for the target are Nuclear receptor subfamily 3 group C member 3, PR, Nr3c3 and Pr (UniProt Q00175). Reported research use falls within the cancer area, with documented subcellular localisation in the nucleus and cytoplasm.

Isoform B of the receptor functions as a transcriptional activator of several progesterone-dependent promoters in a variety of cell types and is involved in activation of SRC-dependent MAPK signalling on hormone stimulation. The encoded protein has a reported molecular weight of 99,074 Da. For research use only.