Mouse Procollagen II N-Terminal Propeptide (PIINP) ELISA Kit

Quantifying a marker of type II collagen biosynthesis in murine samples, this immunoassay from Assay Genie measures Procollagen II N-Terminal Propeptide (PIINP) cleavage products in research applications. PIINP is liberated from the N-terminal propeptide region of procollagen II during extracellular fibril formation, making it a useful indicator of cartilage matrix deposition and chondrocyte biosynthetic activity. Common applications include monitoring disease progression in mouse osteoarthritis models, evaluating fracture callus maturation, characterizing growth plate development, and assessing engineered cartilage constructs.

Supplied as a complete microplate kit sufficient for 96 assays, the package contains pre-coated strip wells, a biotinylated detection antibody, recombinant mouse PIINP standards, streptavidin-HRP conjugate, TMB substrate, and stop reagent. The protocol has been validated with various mouse-origin sample matrices, including serum-derived, plasma-derived, and tissue homogenate preparations. Reagents are shipped on cold packs and should be stored refrigerated between uses to preserve reagent activity. Intended for research use only.