Mouse Procollagen C Proteinase Enhancer 1 (PCPE1) ELISA Kit

This quantitative immunoassay from Assay Genie measures mouse Procollagen C Proteinase Enhancer 1 (PCPE1), a ~50 kDa glycoprotein that potentiates BMP-1/tolloid-type proteinases responsible for C-terminal propeptide cleavage of fibrillar procollagens. Researchers studying collagen fibril assembly, extracellular matrix remodeling, dermal fibrosis, wound healing kinetics, and bone mineralization use this 96-test kit to quantify PCPE1 levels in mouse research samples.

PCPE1 binds the C-propeptide domain of procollagen types I, II, and III through its two CUB domains, accelerating the maturation step that converts soluble procollagen into tropocollagen. The kit includes pre-coated microplate wells, detection antibody, standards, and substrate reagents sufficient for 96 assays, with a colorimetric read-out compatible with standard laboratory plate readers. Mouse reactivity makes the assay useful for preclinical studies of scleroderma, keloid formation, and connective tissue disorders using knockout or transgenic strains.

Each run includes standard curve reagents for interpolation of unknown sample concentrations, and the kit is intended for research use only in laboratory settings. Reconstituted components require refrigerated storage, and unused wells can be resealed for later experiments provided the kit is used within the stated shelf life.