Mouse Prion Protein (PRNP) ELISA Kit

This quantitative immunoassay from Assay Genie measures cellular prion protein (PRNP) levels in mouse-derived samples, supporting neuroscience and prion disease research workflows. The kit targets the PrP^C isoform encoded by the mouse Prnp gene, a glycosylphosphatidylinositol (GPI)-anchored cell-surface glycoprotein most abundant in central nervous system tissue.

Researchers commonly apply this ELISA to study scrapie-infected mouse models, Creutzfeldt-Jakob disease analogues, and other transmissible spongiform encephalopathies, as well as protein misfolding, aggregation kinetics, and neurodegeneration pathways. The kit is formatted as a 96-assay plate and uses a colorimetric read-out compatible with standard microplate readers, supporting high-throughput workflows in academic and pharmaceutical laboratories.

Compatible sample types include tissue homogenates, cell lysates, and related preparations, allowing flexibility for brain, spleen, and peripheral tissue analysis. The assay supports refrigerated storage of components, making it useful for laboratories running longitudinal prion protein studies or screening transgenic and knockout mouse colonies.