Mouse Prepronociceptin (Pnoc) ELISA Kit

Assay Genie provides this Mouse Prepronociceptin (PNOC) ELISA Kit, a Sandwich-format ELISA designed for the accurate measurement of prepronociceptin levels in mouse serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay targets natural and recombinant mouse Prepronociceptin and delivers a detection range of 78-5000pg/mL with a sensitivity of 39.6pg/mL.

Prepronociceptin is listed in UniProt (Q64387) as a secreted precursor that belongs to the opioid neuropeptide precursor family. Nociceptin, derived from this precursor, is the ligand of the opioid receptor-like receptor (OPRL1) and may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. The encoded protein is proteolytically processed to generate multiple biologically active peptides, including nociceptin and nocistatin, which have opposite functions in pain transmission. Prepronociceptin is described as a key protein involved in pain modulation, making it relevant to pain management and analgesic drug development.

This Mouse Prepronociceptin (PNOC) ELISA Kit is intended for research use only and is suited to studies in pain biology, neurology, and drug development. The target protein carries the functional annotation "Orphanin FQ2: Has potent analgesic activity."