Mouse PK2 (Prokineticin 2) ELISA Kit (MOES01391)

Quantitative measurement of mouse Prokineticin 2 (also known as Bv8) is supported by this immunoassay from Assay Genie, supplied as a 96 assays kit for laboratory research use. Prokineticin 2 is a secreted cysteine-rich signaling protein that binds the G-protein coupled receptors PKR1 (GPR73) and PKR2 (GPR73L), mediating diverse physiological and pathological processes across multiple organ systems.

Applications supported by the kit include studies of:

• Circadian rhythm regulation within the suprachiasmatic nucleus, where PK2 functions as a core output signal
• Kallmann syndrome, where loss-of-function mutations in PROK2 cause hypogonadotropic hypogonadism with anosmia
• Angiogenesis and tumor microenvironment research, since PK2 promotes endothelial cell proliferation
• Inflammatory cell chemotaxis and immune cell migration
• Nociception, gastrointestinal motility, and reproductive biology

The kit supports quantification in tissue lysates, cell culture supernatants, and various biological specimens from experimental mouse models. The 96 assays format provides throughput for screening studies. Prokineticin 2 has gained attention as a biomarker candidate in models of myocardial infarction, inflammatory bowel disease, and cancer progression, and this Assay Genie product offers researchers a tool for measuring endogenous mouse PK2 levels in vivo or in cell-based experimental systems.