Mouse Phosphodiesterase 3B, cGMP Inhibited (PDE3B) ELISA Kit

The mouse-specific Phosphodiesterase 3B (PDE3B) immunoassay from Assay Genie delivers quantitative measurement of PDE3B, a cGMP-inhibited phosphodiesterase that regulates cyclic nucleotide turnover in metabolic and cardiovascular tissues. The kit accommodates diverse sample inputs including serum samples, plasma samples, cell lysates, tissue homogenates, and cell culture supernatants, supporting translational research workflows where flexibility in matrix choice matters.

Detection relies on a colorimetric readout, and the kit is supplied in a 96-assay microplate configuration suitable for moderate-throughput screening. PDE3B occupies a central node in insulin and glucagon signaling cascades, so this kit is commonly deployed to investigate adipocyte lipolysis, hepatic glucose output, cardiac myocyte contractility, and the pharmacodynamics of PDE3-selective inhibitors in mouse models of type 2 diabetes, obesity, and heart failure. The assay is validated for mouse reactivity only and is intended for research use only, not for diagnostic procedures.