Mouse Peroxiredoxin-4 (Prdx4) ELISA Kit

A sandwich ELISA kit from Assay Genie designed for the quantitative measurement of mouse Peroxiredoxin-4 (Prdx4). The target is also known by the synonyms Antioxidant enzyme AOE372, Peroxiredoxin IV, Thioredoxin peroxidase AO372, Thioredoxin-dependent peroxide reductase A0372, and Prx-IV. The assay is intended for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and detects natural and recombinant mouse Peroxiredoxin-4 with a reported detection range of 31.2-2000pg/mL and a sensitivity of 10pg/mL.

Peroxiredoxin-4 is an antioxidant enzyme involved in redox regulation of the cell and in modulating the activation of NF-kappa-B in the cytosol via I-kappa-B-alpha phosphorylation. The protein is reported to form a homodimer or a heterodimer with PRDX1, disulfide-linked upon oxidation, and is localised to the cytoplasm and secreted. The associated UniProt entry is O08807, and the listed molecular weight is 31,053 Da. The kit is for research use only.