Mouse Peroxidasin homolog (Pxdn) ELISA Kit

A Sandwich ELISA Kit from Assay Genie for research use, designed for the accurate measurement of mouse peroxidasin homolog (PXDN) levels in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Detection is performed by a colorimetric method, and reactivity is specific to mouse samples.

The kit reports a detection range of 1.56-100ng/mL and a sensitivity of 0.53ng/mL, and is specific for natural and recombinant mouse Peroxidasin homolog. According to the manufacturer, peroxidasin homolog is a key protein involved in oxidative stress and extracellular matrix formation, with dysregulation linked to fibrosis, cancer, and inflammatory disorders, and is highlighted as a potential therapeutic target and biomarker for disease progression.

The target protein displays low peroxidase activity and is likely to participate in H(2)O(2) metabolism and peroxidative reactions in the cardiovascular system, and plays a role in extracellular matrix formation. It is localised to the secreted extracellular space and extracellular matrix, with enrichment in the peritubular space of fibrotic kidneys. The associated research area is signal transduction.