Mouse Peripheral myelin protein 22 (Pmp22) ELISA Kit

Designed for the accurate detection of mouse Peripheral Myelin Protein 22 (PMP22), this sandwich ELISA from Assay Genie targets a key protein involved in peripheral myelination, where it plays a crucial role in maintaining the structure and function of peripheral nerves. Dysregulation of PMP22 has been linked to neurological disorders such as Charcot-Marie-Tooth disease, making it a valuable biomarker for research into these conditions and the development of potential therapeutic interventions.

The assay provides a detection range of 0.625-40ng/mL with a sensitivity of 0.312ng/mL. Precision data show an intra-assay CV of 4.5% and an inter-assay CV of 9.2%. The kit specifically detects natural and recombinant mouse Peripheral myelin protein 22, and PMP22 is described as a cell membrane multi-pass membrane protein that might be involved in growth regulation and myelinization in the peripheral nervous system.

Suitable sample types include serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. The associated UniProt accession is P16646. For research use only.