Mouse Perilipin 1 (PLIN1) ELISA Kit

Perilipin 1 (PLIN1) coats the surface of intracellular lipid droplets in adipocytes and acts as a master regulator of triglyceride storage and lipolysis. Phosphorylation of PLIN1 by protein kinase A releases stored triglycerides for breakdown by cytosolic lipases, making PLIN1 protein levels a direct readout of adipocyte differentiation, lipid storage capacity, and the dynamic state of lipolytic flux in metabolic tissues.

This mouse-specific ELISA kit from Assay Genie uses a two-antibody immunoassay configuration to quantify PLIN1 in tissue homogenates, cell lysates, and assorted body fluids, supporting research into obesity, insulin resistance, and adipocyte biology. Each kit supplies reagents sufficient for 96 determinations run on a standard microplate reader, with results read in the visible spectrum after the enzyme-substrate reaction. The product is intended for research use only and is not validated for diagnostic procedures.

Typical applications include profiling PLIN1 expression in white and brown adipose tissue, evaluating the effects of PPARγ agonists or β-adrenergic stimulation on adipocyte lipid handling, and characterizing mouse models of lipodystrophy and metabolic disease.