Mouse Perforin-1 (Prf1) ELISA Kit

Designed for the accurate measurement of mouse perforin-1 (Prf1), this colorimetric sandwich ELISA from Assay Genie is suited to the detection of the target in serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids.

The assay covers a detection range of 15.6–1000 pg/mL with a sensitivity of 7.8 pg/mL and is specific for both natural and recombinant mouse perforin-1. Listed synonyms for the protein include Cytolysin, Lymphocyte pore-forming protein, P1, and Pfp.

Perforin-1 plays a key role in secretory granule-dependent cell death and in the defense of virus-infected or neoplastic cells, contributing to the cytotoxic activity of T cells and natural killer cells. According to the manufacturer, dysregulation of perforin-1 has been linked to various diseases, including autoimmune disorders, infections, and certain types of cancer, supporting use of the kit as a valuable research tool within immunology. For research use only.