Mouse Pentraxin-3/TSG-14 PharmaGenie ELISA Kit (SBRS1552)

Pentraxin-3 (PTX3), a long pentraxin and acute-phase glycoprotein also known as TNF-stimulated gene 14 (TSG-14), is a pattern-recognition molecule central to innate immunity, complement activation, and the inflammatory response. The biomarker is rapidly induced by pro-inflammatory cytokines such as IL-1β and TNF-α and is secreted by endothelial cells, macrophages, monocytes, and dendritic cells, making it an early indicator of innate immune activation.

The Assay Genie Mouse Pentraxin-3/TSG-14 PharmaGenie ELISA Kit is a 96-assay immunoassay for quantifying mouse PTX3 in cell culture supernatant, plasma, or serum from research subjects. It uses an absorbance-based readout on standard microplate instruments and includes pre-coated plates along with the reagents needed to generate a standard curve for quantitative analysis.

PTX3 is widely studied in cardiovascular disease, sepsis, autoimmune and chronic inflammatory disorders, infectious-disease models, and tumor-microenvironment research. Investigators characterizing vascular inflammation, acute-phase responses, or biomarker discovery in murine models can pair this ELISA with complementary methods such as immunohistochemistry, western blot, flow cytometry, or cell culture-based assays to evaluate inflammatory pathways in tissues and circulation.