Mouse Paraoxonase 1 (PON1) ELISA Kit

Cardiovascular and toxicology research relies on accurate measurement of enzymes that protect circulating lipids from oxidative damage. Paraoxonase 1 (PON1) is a calcium-dependent enzyme synthesized primarily in the liver and carried on high-density lipoprotein particles. It hydrolyzes a range of organophosphate substrates, including paraoxon, and contributes to the antioxidant protection of circulating lipids and LDL. Mouse models are central to PON1 research because the murine enzyme shares substantial functional overlap with the human ortholog; genetic knockouts display altered susceptibility to atherosclerosis, diminished HDL function, and heightened sensitivity to organophosphate toxicity.

This quantitative enzyme-linked immunosorbent assay kit from Assay Genie is configured for measurement of mouse PON1 in laboratory research samples. The microplate-based kit format supports studies in cardiovascular biology, toxicology, metabolic disease, and oxidative stress, and the workflow fits standard laboratory protocols.