Mouse Pannexin-1 (Panx1) ELISA Kit

Manufactured by Assay Genie, this sandwich-format ELISA kit is designed for the precise measurement of pannexin-1 levels in mouse serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. The assay uses a colorimetric detection method and is reactive with mouse samples, with specificity for natural and recombinant mouse Pannexin-1.

Performance characteristics include a detection range of 0.156-10 ng/mL, a sensitivity of 0.08 ng/mL, an intra-assay CV of 6.8%, and an inter-assay CV of 8.7%. Recovery in serum averages 90% (range 84-96%) and in plasma averages 92% (range 86-98%). The kit targets pannexin-1 (UniProt: Q9JIP4), a homohexameric, multi-pass membrane protein of 48,167 Da that functions as a structural component of gap junctions and hemichannels and may play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. It is localised to the cell membrane, cell junctions, gap junctions, and endoplasmic reticulum membrane.

For research use only.