Mouse PAI1/Plasminogen activator inhibitor 1 ELISA Kit

A colorimetric sandwich ELISA from Assay Genie for the quantitative measurement of mouse plasminogen activator inhibitor-1 (PAI-1, SERPINE1) in serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples. The assay uses a double-antibody format with TMB substrate development and a stop reaction read at 450 nm. Standard storage is 2-8°C for 12 months.

PAI-1 is a key regulator of the fibrinolysis pathway, acting as the principal inhibitor of tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA). Dysregulation of PAI-1 has been linked to thrombosis, cardiovascular disease, and fibrosis, making it a target of interest as a biomarker and for potential therapeutic intervention. The kit is designed with high sensitivity and specificity to support reliable and reproducible results across a variety of research applications.

Validation data are provided for serum, EDTA plasma, and heparin plasma, including linearity across serial dilutions and spike-recovery performance in each matrix.