Mouse Osteocalcin (Bglap) ELISA Kit

This immunoassay from Assay Genie quantifies mouse osteocalcin, the bone gamma-carboxyglutamate protein encoded by the Bglap gene. Osteocalcin is a vitamin K-dependent peptide produced by osteoblasts and deposited into the bone matrix, with a portion entering circulation where it serves as a biomarker of bone formation. Investigators studying skeletal biology, age-related bone loss, fracture repair, and metabolic bone disease in murine models apply this kit to measure circulating osteocalcin levels in mouse-derived specimens. Applications include osteoporosis research, assessment of glucocorticoid or diabetic effects on bone, evaluation of therapeutics targeting bone remodeling, and investigation of the endocrine functions linking the skeleton to glucose metabolism and energy homeostasis. The 96-assay format provides sufficient reagents for longitudinal studies tracking bone turnover markers across treatment groups in laboratory mice. Each plate supports quantitative measurement suitable for research use only and in vitro analysis of bone biology endpoints.