Mouse OPG PharmaGenie ELISA Kit (SBRS1493)

Osteoprotegerin (OPG, TNFRSF11B) is a soluble decoy receptor central to the RANK/RANKL/OPG signaling axis that governs osteoclast differentiation and bone resorption. The Mouse OPG PharmaGenie ELISA Kit from Assay Genie provides researchers with a quantitative immunoassay tool to measure OPG concentrations across mouse biological samples, supporting studies of skeletal biology and related disease models.

Calibrated for use with cell culture supernatants, plasma, and serum from mouse specimens, the assay supports preclinical investigations in osteoporosis research, inflammatory arthritis models, periodontal bone loss studies, and vascular calcification, where circulating OPG levels are tracked as indicators of cardiovascular and skeletal health. Researchers studying tumor-bone interactions and metastatic bone disease also use this measurement to characterize how tumor-derived factors reshape the bone microenvironment.

Detection is based on a colorimetric readout that enables absorbance-based quantification using standard microplate readers. The kit includes all reagents required for 96 individual determinations, supporting longitudinal study designs and comparative analyses between treatment cohorts. When paired with RANKL and RANK assays, the OPG measurement helps researchers map the regulatory network controlling osteoclast activity and bone turnover in mouse model systems.