Mouse Nuclear receptor subfamily 5 group A member 2 (Nr5a2) ELISA Kit

This sandwich ELISA from Assay Genie is intended for the quantitative detection of mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), also known by the synonyms Liver receptor homolog 1, LRH-1 and Lrh1. The kit is reactive with mouse samples and has been validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, with specificity for natural and recombinant mouse NR5A2.

Reported performance figures include a detection range of 78-5000pg/mL and a sensitivity of 39.1pg/mL. NR5A2 is a nuclear-localised transcription factor of the nuclear hormone receptor family that binds the promoter sequence element 5'-AACGACCGACCTTGAG-3', regulating gene expression in liver and pancreas and contributing to embryonic development. The protein binds DNA as a monomer and interacts with GRIP1, NCOA2 and NR0B2. Dysregulation of NR5A2 has been linked to metabolic disorders, liver diseases and cancer, supporting its use as a biomarker in disease research.

The corresponding UniProt entry is P45448, with a molecular weight of 64,020 Da. For research use only.