Mouse Nr1h3  (Oxysterols receptor LXR-alpha) ELISA Kit (MOFI01358)

Liver X receptor alpha (LXR-alpha), encoded by the Nr1h3 gene, is a nuclear receptor that senses oxidized cholesterol derivatives and orchestrates transcriptional programs controlling lipid homeostasis, reverse cholesterol transport, and inflammatory responses. The Assay Genie Mouse Nr1h3 ELISA Kit enables researchers to quantify this receptor in mouse-derived samples, supporting mechanistic studies in atherosclerosis, non-alcoholic fatty liver disease, obesity, and immune regulation.

This in vitro immunoassay is intended for research use only and includes the reagents and protocol needed to perform the assay. The kit is supplied in a 96 Assays format and uses an absorbance-based chromogenic readout on pre-coated plate wells. Researchers working with serum or plasma preparations from mouse models can apply the assay to track changes in LXR-alpha expression under different dietary, pharmacological, or genetic interventions. Each kit includes detection antibody, standards, substrate, buffers, and a detailed product insert with reconstitution and storage guidance.

By providing a quantitative readout of LXR-alpha protein levels, this kit complements gene expression, western blot, and flow cytometry workflows in murine systems. Laboratories investigating nuclear receptor pharmacology, cholesterol efflux pathways, or macrophage polarization in mouse models will find the Mouse Nr1h3 ELISA Kit from Assay Genie a practical addition to their immunoassay toolbox.