Mouse Non-receptor tyrosine-protein kinase TYK2 (Tyk2) ELISA Kit

Built for quantitative detection of mouse non-receptor tyrosine-protein kinase TYK2, this sandwich ELISA from Assay Genie is specific for the natural and recombinant mouse TYK2 protein (UniProt Q9R117). The assay reports a detection range of 0.625-40ng/mL and a sensitivity of 0.313ng/mL, and it is intended for research use only. Compatible sample types include serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.

TYK2 is a member of the JakA family of non-receptor tyrosine-protein kinases. According to the manufacturer's functional description, it is involved in intracellular signal transduction by amplifying type I and type II IFN signaling, and it phosphorylates the interferon-alpha/beta receptor alpha chain. The protein plays an essential role in promoting selective immune responses, including innate host defense mechanisms and specific antiviral activities, and the supplied documentation lists an interaction with JAKMIP1.

Configured for mouse reactivity with a colorimetric ELISA readout, the kit supports studies of TYK2 function within immune signalling pathways and related research applications.