Mouse Nociceptin PharmaGenie ELISA Kit (SBRS0072)

Quantify endogenous nociceptin (Orphanin FQ) in murine samples with this competitive ELISA from Assay Genie. Part of the PharmaGenie reagent line, the kit targets the 17-amino acid neuropeptide that functions as the natural ligand for the NOP/ORL1 receptor, an atypical member of the opioid receptor family that modulates pain perception, stress responses, anxiety-like behavior, and reward-driven neural circuits. The competitive immunoassay format is selected over a dual-antibody capture design because nociceptin's small molecular size prevents simultaneous binding by two separate antibodies.

Validated for cell culture supernatant samples and for samples derived from murine blood including plasma fractions and serum fractions, the assay supports both in vitro pharmacological studies and in vivo behavioral neuroscience investigations of addiction, analgesia, and mood-related disorders. Each kit provides reagents for 96 assays in a colorimetric microplate format and is labeled for research use only, not for diagnostic or clinical applications.