Mouse Neogenin (Neo1) ELISA Kit

Manufactured by Assay Genie, this Sandwich ELISA kit enables quantitative measurement of mouse Neogenin (Neo1) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. Intended for research use only, it supports studies in neurosciences, with applications in neuronal development, axon guidance, and cell migration research.

The assay is validated for mouse samples and uses a colorimetric detection method. It reports a detection range of 0.156-10ng/mL with a sensitivity of 0.091ng/mL, and demonstrates specificity for natural and recombinant mouse Neogenin. Reagent components are stored at -20°C and 4°C as indicated in the kit.

Neogenin (UniProt P97798) is a multi-functional cell surface receptor that regulates cell adhesion across developmental processes including neural tube and mammary gland formation, myogenesis, and angiogenesis. It serves as a receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families; netrin-Neogenin interactions produce a chemoattractive axon guidance response and cell-cell adhesion, while interactions with RGMa and RGMb produce a chemorepulsive response.