Mouse NEFL (Neurofilament light polypeptide) ELISA Kit (MOFI01432)

Neurofilament light polypeptide (NEFL) is a 68 kDa cytoskeletal intermediate filament protein abundantly expressed in myelinated axons, and its quantification in murine biofluids provides a sensitive read-out of axonal injury in preclinical neuroscience research. The Mouse NEFL ELISA Kit from Assay Genie delivers this measurement in a 96 Assays microplate configuration with colorimetric readout, supporting studies of neurodegeneration, neuronal damage, and biomarker discovery in mouse models.

This immunoassay is widely used to investigate disease mechanisms and therapeutic interventions in models of Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis, traumatic brain injury, and peripheral neuropathy, enabling translational comparison with human neurofilament light chain measurements in cerebrospinal fluid and peripheral blood. Frozen aliquot handling and refrigerated storage preserve antibody binding activity through multiple freeze-thaw cycles, accommodating longitudinal study designs.

Each pack includes pre-coated plate wells and ready-to-use reagents in a single-use configuration that supports batch processing across study cohorts. Assay Genie formats the kit for research use only applications, allowing investigators to evaluate treatment effects, disease progression, and pharmacodynamic responses in cell culture supernatant, tissue homogenate, and other matrices derived from mouse experimental systems.