Mouse Natriuretic peptides A (Nppa) ELISA Kit

Assay Genie offers this ELISA kit designed for the quantitative measurement of mouse Natriuretic Peptides A (NPPA) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay detects both natural and recombinant mouse NPPA and is intended for research use only.

Performance characteristics include a detection range of 15.6-1000pg/mL and a sensitivity of 7.86pg/mL. NPPA, also known by the synonyms Prepronatriodilatin and Pnd (UniProt P05125), is a secreted hormone involved in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation; it specifically binds and stimulates cGMP production of the NPR1 receptor and also binds the clearance receptor NPR3.

By enabling accurate measurement of NPPA levels, the kit supports research into cardiovascular health and disease, hypertension, blood pressure regulation and fluid balance, where NPPA serves as an important biomarker for studying pathophysiology and identifying potential therapeutic targets.