Mouse NAD-dependent protein deacylase sirtuin-5, mitochondrial (Sirt5) ELISA Kit

This colorimetric Sandwich ELISA Kit from Assay Genie is designed for the quantitative measurement of mouse NAD-dependent protein deacylase sirtuin-5, mitochondrial (Sirt5) in research samples. Validated for mouse reactivity, the kit is compatible with serum, plasma, and cell culture supernatant samples and is intended for research use only.

Sirtuin 5 is a key enzyme involved in mitochondrial metabolism and regulation, contributing to cellular energy production and stress response. Dysregulation of Sirt5 has been associated with metabolic disorders, neurodegenerative conditions, and cancer, making it a valuable target for investigating disease mechanisms and potential therapeutic strategies.

The kit is supplied with a dismountable ELISA microplate, lyophilized standard, sample and assay diluents, detection reagents, wash buffer, substrate, stop solution, and plate sealers. Components are stored at -20°C or 4°C as indicated. The target analyte, Sirt5, is an NAD-dependent deacetylase localized to the mitochondrion, with UniProt accession Q8K2C6 and NCBI Gene ID 68346. The protein has a reported molecular weight of 34,134 Da.