Mouse Myotrophin (MTPN) ELISA Kit

Cardiac hypertrophy research depends on accurate quantification of mediators such as myotrophin, and the Assay Genie Mouse Myotrophin (MTPN) ELISA Kit enables measurement of this 12 kDa cytoplasmic protein in mouse-derived samples. Myotrophin was originally isolated from hypertrophied rat myocardium, where it stimulates cardiac myocyte growth and protein synthesis. The protein also participates in NF-kB pathway activation and has been investigated in the context of diabetic cardiomyopathy, skeletal muscle differentiation, and cardiovascular remodeling.

The kit reacts specifically with murine MTPN and supports in vitro research workflows, including comparisons between wild-type and knockout tissues, time-course studies of pressure-overload or transaortic constriction models, and profiling of metabolic or genetic cardiomyopathy phenotypes. The assay follows a standard ELISA workflow, and the chromogenic end-point enables data acquisition on a conventional microplate reader.

Each kit provides reagents for 96 individual determinations. Intended for research use only, this Assay Genie product fits basic and translational laboratories focused on cardiac signaling, hypertrophy mechanisms, and muscle physiology in murine systems.