Mouse Myelin proteolipid protein (Plp1) ELISA Kit

Assay Genie offers a Sandwich ELISA kit for the quantitative measurement of mouse myelin proteolipid protein (Plp1), described as the major myelin protein of the central nervous system. The kit is positioned for research into neurological conditions such as multiple sclerosis, where PLP1 is a relevant biomarker.

Reported specifications include a detection range of 0.156-10ng/mL and a sensitivity of 0.087ng/mL. The assay is reactive with mouse samples and is validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. It detects natural and recombinant mouse PLP1. Listed synonyms for the target are Lipophilin, PLP, and Plp, with the corresponding UniProt entry P60202. Subcellular localisation is given as the cell membrane (a multi-pass membrane protein) and the myelin membrane, with co-localisation with SIRT2 in internodal regions, at paranodal axoglial junctions and Schmidt-Lanterman incisures of the myelin sheath.

The product is supplied for research use only, with intra-assay CV, inter-assay CV, linearity and recovery data provided with the kit.