Mouse Mothers against decapentaplegic homolog 4 (Smad4) ELISA Kit

This sandwich ELISA kit from Assay Genie is designed for the quantitative detection of mouse Mothers against decapentaplegic homolog 4 (SMAD4) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay is reactive with mouse samples and is suited to research applications in cancer and studies of TGF-beta signalling, where SMAD4 acts as a co-SMAD and mediator of signal transduction by TGF-beta, with roles in regulating cell growth, differentiation and apoptosis. Synonyms for the target recognised by the kit include SMAD family member 4, Deletion target in pancreatic carcinoma 4 homolog, MAD homolog 4, Dpc4 and Madh4.

Performance characteristics include a detection range of 0.312-20ng/mL and a sensitivity of 0.168ng/mL, with specificity for natural and recombinant mouse SMAD4. The kit is supplied in a solid-phase format, with components stored at –20 °C (and some at 4 °C) and shipped at +4 °C. The associated UniProt entry is P97471 and the protein has a molecular weight of 60kDa.