Mouse Mast/stem cell growth factor receptor Kit (Kit) ELISA Kit

Assay Genie supplies a Sandwich ELISA Kit intended for the quantitative measurement of mouse mast/stem cell growth factor receptor Kit, also referred to as Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, CD117, and SCFR. The kit is suitable for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, and is for research use only.

Manufacturer specifications report a detection range of 0.156-10ng/mL and a sensitivity of 0.083ng/mL. Precision values are 6.3% intra-assay CV and 10.8% inter-assay CV. Linearity was demonstrated in serum (103-113% to 99-108% across 1:2 to 1:16 dilutions), EDTA plasma (97-109% to 104-112%), and heparin plasma (90-100% to 107-118%). Spike recovery averaged 106% (range 100-112%) in serum and 108% (range 102-114%) in plasma.

The assay recognises natural and recombinant mouse mast/stem cell growth factor receptor Kit, a tyrosine-protein kinase that functions as the cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, and mast cell development, with relevance to research in cancer, autoimmune disorders, and inflammatory diseases (UniProt: P05532). Exact storage conditions for individual components are provided with the kit.