Mouse Lysyl-tRNA synthetase (Kars) ELISA Kit

A high-quality sandwich ELISA from Assay Genie, this kit enables the precise measurement of lysyl-tRNA synthetase (Kars) levels in mouse serum, plasma, and cell culture supernatants, and also supports analysis of tissue homogenates and other biological fluids. Lysyl-tRNA synthetase is a key enzyme that catalyzes the specific attachment of lysine to its cognate tRNA during protein synthesis: the amino acid is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Dysregulation of this enzyme has been implicated in various diseases, including cancer, neurodegenerative disorders, and autoimmune conditions, making the assay a valuable tool for studying its role in disease pathology and potential therapeutic targets.

The assay has a detection range of 0.312-20ng/mL and a sensitivity of 0.156ng/mL. It is specific for natural and recombinant mouse Lysine--tRNA ligase, with read-out by colorimetric detection. The associated UniProt entry is Q99MN1, and the reported molecular weight is 67,840 Da. The subcellular location is the cytoplasm. For research use only.