Mouse Lysyl Oxidase Like Protein 2 (LOXL2) ELISA Kit

Colorimetric immunoassay from Assay Genie enables quantitative measurement of mouse Lysyl Oxidase Like Protein 2 (LOXL2) in research specimens, with validation for use on murine serum samples, plasma preparations, and tissue homogenates. LOXL2 is a copper-dependent amine oxidase that catalyzes the oxidative deamination of peptidyl lysine residues, driving collagen and elastin crosslinking within the extracellular matrix. Aberrant LOXL2 expression has been documented in hepatic, pulmonary, and renal fibrotic remodeling, as well as in tumor invasion and metastatic niches, making reliable quantification in murine systems central to translational research.

The kit is configured for 96 reactions and is intended for research use only, with readouts on standard microplate readers. Application areas include extracellular matrix biology, epithelial-mesenchymal transition studies, fibrosis modeling, and pathway-targeted therapeutics evaluation in mouse models of disease. Each kit contains a pre-coated microplate, calibration standards, detection antibody, and reagents needed to construct a standard curve, with protocols arranged to minimize hands-on time and inter-assay variability. Storage and handling recommendations supplied with the kit should be observed to preserve reagent performance across multiple thaw cycles.