Mouse Lipopolysaccharide Binding Protein (LBP) ELISA Kit

Innate immunity to gram-negative bacteria depends on lipopolysaccharide binding protein (LBP), a hepatic acute-phase glycoprotein that catalyzes transfer of LPS monomers to membrane-bound CD14 on myeloid cells. Mouse LBP concentrations in research samples can be quantified using this colorimetric enzyme-linked immunosorbent assay from Assay Genie, formatted as a 96-assay kit.

Investigators studying endotoxemia, polymicrobial sepsis, acute liver injury, and chronic inflammatory disease use murine LBP measurement to track systemic innate immune activation, evaluate therapeutic candidates that modulate TLR4 signaling, and characterize knockout or transgenic mouse strains under controlled LPS challenge. The assay accepts mouse-derived sample matrices including whole-blood derivatives and tissue-culture supernatants from primary cell isolates.

Storage temperature and shelf life are detailed in the product insert; reagents should be kept refrigerated between uses. For research use only.